Abstract: This paper focuses on analysing the influence of geometric design characteristics on traffic safety using bi-directional data on a divided roadway operated under heterogeneous traffic conditions in India. The study was carried out on a four lane divided inter-city highway in plain and rolling terrain. Statistical modelling approach by Poisson regression and Negative binomial regression were used to assess the safety performance as occurrence of crashes are random events and to identify the influence of the geometric design variables on the crash frequency. Negative binomial regression model was found to be more suitable to identify the variables contributing to road crashes. The study enabled better understanding of the factors related to road geometrics that influence road crash frequency. The study also established that operating speed has a significant contribution to the total number of crashes. Negative binomial models are found to be appropriate to predict road crashes on divided roadways under heterogeneous traffic conditions.